You know a lot about Oprah. There are two things I find amazing and anyone can change his or her life by doing what Oprah did:
1) She learned to read at 3 and has made this a lifetime passion.
The ability to read. It's a life-changer.
2) When her grandmother was teaching her how to do white people's laundry, she decided that that was not going to be her life.
The power of the mind to change things. Embrace it, harness it and you can change most everything.